Related Articles from the A∙WOL Consortium
Inflammation, pathogenesis, adverse reaction
Debrah AY, Mand S, Marfo-Debrekyei Y, Batsa L, Pfarr K, Lawson B, Taylor MJ, Adjei O, Hoerauf A. (2009) Reduction in levels of plasma vascular endothelial growth factor-A and improvement in hydrocele patients by targeting endosymbiotic Wolbachia sp. in Wuchereria bancrofti with doxycycline. American Journal of Tropical Medicine and Hygiene, 80 (6):956-63.
Turner JD, Langley RS, Johnston KL, Gentil K, Ford L, Wu B, Graham M, Sharpley F, Slatko B, Pearlman E, Taylor MJ. (2009) Wolbachia lipoprotein stimulates innate and adaptive immunity through toll-like receptors 2 and 6 (TLR2/6) to induce disease manifestations of filariasis. The Journal of Biological Chemistry, 284 (33):22364-78.
Kluxen G, Hoerauf A. (2008) The significance of some observations on African ocular onchocerciasis described by Jean Hissette (1888-1965). Bulletin de la Société Belge d'ophtalmologie (307):53-8.
Korten S, Badusche M, Büttner DW, Hoerauf A, Brattig N, Fleischer B. (2008) Natural death of adult Onchocerca volvulus and filaricidal effects of doxycycline induce local FOXP3+/CD4+ regulatory T cells and granzyme expression. Microbes & Infection, 10 (3):313-24.
Debrah AY, Mand S, Toliat MR, Marfo-Debrekyei Y, Batsa L, Nürnberg P, Lawson B, Adjei O, Hoerauf A, Pfarr KM. (2007) Plasma vascular endothelial growth Factor-A (VEGF-A) and VEGF-A gene polymorphism are associated with hydrocele development in lymphatic filariasis. American Journal of Tropical Medicine & Hygiene, 77 (4):601-8.
Gillette-Ferguson I, Daehnel K, Hise AG, Sun Y, Carlson E, Diaconu E, McGarry HF, Taylor MJ, Pearlman E. (2007) Toll-like receptor 2 regulates CXC chemokine production and neutrophil recruitment to the cornea in Onchocerca volvulus/Wolbachia-induced keratitis. Infectious Immunology, 75 (12):5908-15.
Hise AG, Daehnel K, Gillette-Ferguson I, Cho E, McGarry HF, Taylor MJ, Golenbock DT, Fitzgerald KA, Kazura JW, Pearlman E. (2007) Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM. Journal of Immunology, 178:1068-76.
Suba N, Shiny C, Taylor MJ, Narayanan RB. (2007) Brugia malayi Wolbachia hsp60 IgG antibody and isotype reactivity in different clinical groups infected or exposed to human bancroftian lymphatic filariasis. Experimental Parasitology, 116 (3):291-5.
Debrah AW, Mand S, Specht S, Marfo Y, Batsam L, Pfarr K, Larbi J, Lawson B, Taylor MJ, Adjei O, Hoerauf A. (2006) Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in Lymphatic Filariasis. PLoS Pathogens, 2 (9): e92.
Gillette-Ferguson I, Hise AG, Sun Y, Diaconu E, McGarry HF, Taylor MJ, Pearlman E. (2006) Wolbachia- and Onchocerca volvulus-Induced Keratitis (River Blindness) Is Dependent on Myeloid Differentiation Factor 88. Infection and Immunity, 74: 2442-2445.
Turner JD, Langley RS, Johnston KL, Egerton GL, Wanji S, Taylor MJ. (2006) Wolbachia endosymbiotic bacteria of Brugia malayi mediate macrophage tolerance to TLR and CD40 specific stimuli in a MyD88/TLR2-dependent manner. Journal of Immunology, 7: 1240-9.
Turner JD, Mand S, Debrah AY, Muehlfeld J, Pfarr KM, McGarry HF, Adjei O, Taylor MJ, Hoerauf A. (2006) A Randomised, Double Blind Clinical Trial of Three Week Doxycycline Plus Albendazole and Ivermectin in the Treatment of Wuchereria bancrofti, Clinical Infectious Diseases, 42: 1081-1089.
Brattig NW, Bazzocchi C, Kirschning CJ, Reiling N, Büttner DW, Ceciliani F, Geisinger F, Hochrein H, Ernst M, Wagner H, Bandi C, Hoerauf A. (2004) The major surface protein of Wolbachia endosymbionts in filarial nematodes elicits immune responses through TLR2 and TLR4. Journal of Immunology, 173 (1):437-45.
Gillette-Ferguson I, Hise AG, McGarry HF, Turner JD, Esposito A, Sun Y, Diaconu E, Taylor MJ, Pearlman E. (2004) Wolbachia-induced neutrophil activation in a mouse model of ocular onchocerciasis (river blindness). Infection and Immunity. 72 (10):5687-92.
Keiser PB, Reynolds SM, Awadzi K, Ottesen EA, Taylor MJ, Nutman TB. (2002) Bacterial endosymbionts of Onchocerca volvulus in the pathogenesis of posttreatment reactions. Journal of Infectious Diseases, 185 (6):805-11.
Saint Andre A, Blackwell NM, Hall LR, Hoerauf A, Brattig NW, Volkmann L, Taylor MJ, Ford L, Hise AG, Lass JH, Diaconu E, Pearlman E. (2002) The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness. Science, 295 (5561):1892-5.
Brattig NW, Büttner DW, Hoerauf A. (2001) Neutrophil accumulation around Onchocerca worms and chemotaxis of neutrophils are dependent on Wolbachia endobacteria. Microbes & Infection, 3 (6):439-46.
Cross HF, Haarbrink M, Egerton G, Yazdanbakhsh M, Taylor MJ. (2001) Severe reactions to filarial chemotherapy and release of Wolbachia endosymbionts into blood. Lancet, 358 (9296):1873-5.
Bazzocchi C, Ceciliani F, McCall JW, Ricci I, Genchi C, Bandi C. (2000) Antigenic role of the endosymbionts of filarial nematodes: IgG response against the Wolbachia surface protein in cats infected with Dirofilaria immitis. Proceedings Biological Sciences, 267 (1461):2511-6.
Taylor MJ, Cross HF, Bilo K. (2000) Inflammatory responses induced by the filarial nematode Brugia malayi are mediated by lipopolysaccharide-like activity from endosymbiotic Wolbachia bacteria. Journal of Experimental Medicine, 191 (8):1429-36.